Clinical Correlates Of Sleep Problems In Systemic Sclerosis: The Prominent Role Of Pain PDF Print E-mail
Sunday, 16 January 2011 21:39
Objective. Problems with sleep are common in patients with SSc and impact daily function. Little research, however, has examined factors associated with sleep disruption in SSc. Therefore, the objective of this study was to investigate socio-demographic and medical factors associated with sleep disruption in SSc.

Methods. Cross-sectional study of 70 patients from one Canadian Scleroderma Research Group site who were assessed with a 100-mm sleep disruption visual analogue scale (VAS). Patients also completed measures of pain and depressive symptoms and underwent clinical histories and medical examinations. Pearson’s correlations were used to assess bivariate association of socio-demographic and medical variables with sleep VAS scores. Multivariable associations of socio-demographic (Step 1) and medical (Step 2) variables with sleep VAS scores were assessed using hierarchical multiple linear regression.

Results. The mean (S.D.) sleep disruption VAS score was 38.5 (29.9). In bivariate analyses, sleep disruption was associated with marital status (r =0.24, P = 0.042), smoking (r = 0.27, P = 0.025), gastrointestinal symptoms (r = 0.27, P = 0.023), breathing problems (r = 0.31, P = 0.009), pain (r = 0.53, P<0.001) and symptoms of depression (r = 0.34, P = 0.004). In multivariate analysis, only marital status (standardized  =0.24, P = 0.049) and pain (standardized  = 0.50, P<0.001) were significantly associated with sleep disruption.

Conclusion. Sleep disruption scores were as high in SSc as in RA and higher than in the general population. Pain was robustly associated with sleep disruption. Additional research is needed on sleep in SSc so that well-informed sleep interventions can be developed and tested.

Login to download your own copy of the full and original article from the link provided below

 
More articles :

» Scleroderma May Be Initated By Cancer

has reported that researchers at have discovered that some cases of are likely to have been initiated by Cancer.  In a landmark paper published in Science, researchers focusing on a select group of patients with both Scleroderma and Cancer,...

» Important Information About Autoimmune Diseases

There are more than 100 known autoimmune disorders, including rheumatoid arthritis, type 1 diabetes, scleroderma, and lupus. Normally, your immune system is designed to protect your health. But in some people, the immune system creates...

» Neutrophil Elastase Regulator Needed in Systemic Sclerosis

, which promotes and fibrosis, is suspected of playing a role in (SSc). Theresa C. Barnes, MD, from University of Liverpool, Aintree University Hospital, United Kingdom, and colleagues  of Rheumatology that the problem may not be too...

» Juvenile Scleroderma Progression Similar To Adult Onset

The pattern and course of disease in patients who develop systemic sclerosis in childhood or adolescence is similar to that in patients who develop the disease as adults, data from Europe has shown.There were 60 patients among 5,000 included in the...

» The Incidence Of Prostate Cancer Higher In Men With Autoimmune Diseases

Men with autoimmune diseases have a higher incidence of (PCa) than those without those diseases, according to study findings presented at the annual meeting.Using the National Inpatient Sample database, researchers obtained data on 189,290 men...

» Cancer Risk Among Patients With Systemic Sclerosis: A Nationwide Population Study In Taiwan

C-F Kuo, S-F Luo, K-H Yu, I-J Chou, W-Y Tseng, H-C Chang, Y-F Fang, M-J Chiou, L-C SeePosted online on December 11, 2011Objectives: Systemic sclerosis (SSc) has been associated with high cancer risk. We compared the cancer risk among SSc patients...