|Managing Your Digical Ulcer|
|Thursday, 19 August 2010 12:19|
Around 40% of patients with Scleroderma develop open sores on their fingertips called digital ulcers. In some patients, this is the major ongoing difficulty whereas in others, digital ulcers are an uncommon and short term complication.
Digital ulcers occur because of poor blood flow to the fingertips which is in turn related to the narrowing of blood vessels that is the hallmark of all forms of Systemic Scleroderma.
Digital ulcers are tightly linked with Raynaud's phenomenon. They both occur in Scleroderma because of narrowed blood vessels. Raynaud attacks occur daily and are clearly worsened by cold weather. Digital ulcers can occur at anytime of the year and in any weather.
The fingertips in Scleroderma should be cared for in much the way a patient with diabetes might care for their feet.
The Scleroderma research community is actively investigating treatments for digital ulcers. In Europe, intravenous iloprost (Ilomedin®) is approved and widely used, although this therapy is not available in the U.S. Recent studies with bosentan (Tracleer®), an agent approved by the FDA for pulmonary hypertension, have suggested an effect in preventing digital ulcers. Other research projects are in early stages of planning.
Source: University of Michigan Health System