Scleroderma Drug In Development PDF Print E-mail
Friday, 16 October 2009 10:57
According to The Commercial Appeal, arGentis Pharmaceutical has partnered with Shattuck Hammond Partners, the health care investment arm of Morgan Keegan and Co. Inc., to jump-start a capital campaign to raise $12 million to $15 million. ArGentis shelved the campaign last year when the economy soured.

The money will help continue a three-year effort by arGentis to shepherd a treatment for Scleroderma, an autoimmune disease that affects blood vessels and connective tissue. Ted Townsend, the company's vice president of business development, said the treatment could be on the market as early as 2013.

The company has just finished reviewing the treatment's previous clinical trial. The next trial will be the drug's last before it heads to the Food and Drug Administration for market approval. To help that process along, arGentis has assembled a "dream team" to serve on its scientific advisory board.

For example, new board member Maureen D. Mayes wrote "The Scleroderma Book" in 1999. University of California Los Angeles professor Daniel Furst, Georgetown School of Medicine professor Virginia D. Steen and UCLA biostatistics professor Weng Kee Wong also joined the arGentis scientific advisory board.

"These physicians understand this disease process better than anyone in the world," said Townsend. "Their participation in the trial shows the validity of our therapy and will hopefully reinforce our credibility to regulatory authorities."

However, Charles Spaulding, vice president of communications with the Scleroderma Research Foundation, said the disease largely flies under national research radar.

"There's not enough researchers looking at the disease and not enough money being spent on Scleroderma research," Spaulding said.

ArGentis' Scleroderma treatment received "orphan status" in the United States and in the European Union. The designation gives the company market exclusivity for seven years here and 10 years in Europe.

Townsend said the treatment could be a $1 billion annual opportunity in the U.S. and Europe.

The company also has license agreements in hand for about 50 markets globally.

To view the full article, click here.
 
More articles :

» Pressure and Pain In Systemic Sclerosis/ Scleroderma

Begonya Alcacer-Pitarch, Maya H Buch, Janine Gray, Christopher P Denton, Ariane Herrick, Nuria Navarro-Coy, Howard Collier, Lorraine Loughrey, Sue Pavitt, Heidi J Siddle, Jonathan Wright, Philip S Helliwell, Paul Emery, Anthony C RedmondStudy...

» Low-Dose Naltrexone for Pruritus in Systemic Sclerosis

Tracy Frech, Kirsten Novak, Monica P. Revelo, Maureen Murtaugh, Boaz Markewitz, Nathan Hatton, Mary Beth Scholand, Edward Frech, David Markewitz, and Allen D. SawitzkeReceived 31 May 2011; Accepted 14 July 2011Systemic sclerosis (SSc; scleroderma)...

» arGentis Issued Key Patent Related to Treating Fibrosing Diseases by Induction of Immune Tolerance

arGentis Pharmaceuticals, LLC today announced the issuance of United States patent 7,718,765, entitled “Methods for Treating Fibrosing Diseases by Induction of Immune Tolerance." The issued patent, based on the seminal research of Arnold E....

» Scleroderma Research Foundation To Host Patient Webinar Series

The announced the first in a series of free informational Webinars for people living with and others directly or indirectly affected by the disease. The first Webinar will highlight new clinical trials and results from recent studies.The 2011/2012...

» Quality Indicator Sets For Scleroderma

Despite the increasing awareness of Scleroderma (SSc), it continues to have a detrimental effect of the quality of health and lives of those with it. The medical community has recognized that although early treatment of can have a substantial...

» Systemic Sclerosis (Scleroderma)

Panayiotis G. Vlachoyiannopoulos1November 2001Systemic sclerosis (SSc) is an autoimmune systemic disease characterized by small vessel involvement that leads to tissue ischemia and fibroblast stimulation resulting in accumulation of collagen...